流行病学(留学生与双语教学用)（英文版）（普通高等教育“十二五”规划教材·全国高等pdf/txt下载_在线阅读全文

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本教材系统地介绍了流行病学的基本原理和方法，内容简明易懂，每章后面附有重要专业词汇和部分练习题，适合初学流行病学的临床医学专业的留学生和本科生双语教学作为入门教材，也可以作为其他医学相关专业，如护理学、口腔医学、药学、公共卫生服务等专业的学生学习流行病学的教材。本教材也可以供卫生专业工作人员学习和应用流行病学参考。

目　　录

Contents
Part OneFundamental Epidemiology
Chapter 1Introduction
1. What is epidemiology?
2. Brief history of epidemiology
3. An overview of methods of epidemiologic studies
4. Goals of epidemiology
5. Natural history of disease
6. Epidemiology and three levels prevention
7. Epidemiology and clinical medicine
Summary
Study Questions
References
Chapter 2Measures in Epidemiology and Sources of Data

Contents 
Part OneFundamental Epidemiology 
Chapter 1Introduction 
1. What is epidemiology? 
2. Brief history of epidemiology 
3. An overview of methods of epidemiologic studies 
4. Goals of epidemiology 
5. Natural history of disease 
6. Epidemiology and three levels prevention 
7. Epidemiology and clinical medicine 
Summary 
Study Questions 
References 
Chapter 2Measures in Epidemiology and Sources of Data 
1. Introduction to measures in epidemiology 
2. Measures of disease occurrence 
3. Other descriptive population health measures 
4. Sources of data 
Summary 
Study Questions 
References 
Chapter 3Communicable Diseases 
1. What is a communicable disease? 
2. Some key concepts of communicable diseases 
3. Approaches to the control of communicable disease 
4. Infectious disease process 
5.The descriptive epidemiology of communicable disease 
6. Public health surveillance 
7. Epidemic or outbreak investigation 
Summary 
Study Questions 
References 
Chapter 4Survey and Crosssectional Studies 
1. Introduction 
2. Steps in designing and conducting a survey 
3. Sampling 
4. Data gathering approaches 
5. Biases in health surveys 
6. Advantages and pitfalls associated with crosssectional studies 
Summary 
Study Questions 
References 
Chapter 5Cohort Studies 
1. What is a cohort study 
2. Design of cohort study 
3. Cohort selection 
4. Data collection 
5. Analysis and result interpretation 
6. Sample size consideration for a cohort study 
7. Potential biases in cohort studies 
8. Advantages and disadvantages of a cohort study 
Summary 
Study Questions 
References 
Chapter 6Casecontrol Studies 
1. What is casecontrol study? 
2. Design of casecontrol study 
3. Data analysis 
4. Biases in casecontrol study 
5. Sample size consideration 
6. Advantage and problems of casecontrol study 
7. Nested casecontrol study: brief introduction 
8. Comparison of characteristics of casecontrol study and cohort study 
Summary 
Study Questions 
References 
Chapter 7Experimental Studies 
1. Introduction 
2. Example of clinical trials 
3. Study designs for randomized controlled trial 
4. Sample size consideration 
5. Analysis and result interpretation 
6. Advantages and disadvantages of experimental studies and compliance 
7. Ethical aspects of experimentation with human subjects 
8. Assessing the quality of a trial 
Summary 
Study Questions 
References 
Chapter 8Association and Causation 
1. Concept of cause in epidemiology 
2. Association and causal association 
3. Evaluating causal association 
Summary 
Study Questions 
References 
Chapter 9Bias and Confounding 
1. Introduction 
2. Overview of bias 
3. Impact of bias 
4. Confounding 
Summary 
Study Questions 
References 
Chapter 10Screening and Early Detection 
1. Introduction to screening and early detection 
2.   Criteria for establishing a screening program 
3. Population screening tools 
4.   Validity, reliability and error 
5.  Evaluation of screening programs 
Summary 
Study Questions 
References 
Part TwoApplications of Epidemiology 
Chapter 11Application of Epidemiology in Clinical Practice 
1. Prognosis 
2. Clinical decision analysis 
3. Evidencebased medicine 
References 
Chapter 12Molecular and Genetic Epidemiology 
1. Definitions and distinction 
2. Study methods 
References 
Chapter 13Application of Epidemiology on Public Health Service 
1. Public health and public health operations 
2. Epidemiological model of the delivery of health care services 
3. Epidemiology and the public policy process 
4. Translational research and translational epidemiology 
References 
Chapter 14Descriptive Epidemiology in Cancer: Measures of the 
Cancer Burden 
1. Cancer incidence and prevalence 
2. Cancer mortality 
3. Survival rates 
4. Temporal trends 
5. Geographic variation of cancer 
References

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前　　言

Preface

The main goal of public health is to prevent and control disease in human populations. To reach this goal, we attempt to understand the nature of diseases, explore the causes of diseases, take action (public health programs) and evaluate the effectiveness of the actions. Epidemiology plays a crucial role in realizing this goal and deciding which public health programs to develop as well as in evaluating those programs.

Preface 
 
The main goal of public health is to prevent and control disease in human populations. To reach this goal, we attempt to understand the nature of diseases, explore the causes of diseases, take action (public health programs) and evaluate the effectiveness of the actions. Epidemiology plays a crucial role in realizing this goal and deciding which public health programs to develop as well as in evaluating those programs. 
In recent decades, it appears that epidemiology has increasingly become a very important approach, not only for public health but also for clinical medicine and other areas of medical research and practice. Advances in computer design and availability and the development of advanced statistical methods and readily accessible powerful software have made it feasible to manage and statistically analyze very large databases. Epidemiological techniques have been applied to many areas of biomedical research and as a result, quite a few branches of epidemiology have emerged. Today, you might find epidemiologists who specialize in chronic disease or infectious disease epidemiology or in genetic epidemiology or in molecular epidemiology or in pharmacoepidemiology or nutritional epidemiology, to name only a few of the specialties. 
The aim of this book is to provide an overview of principles of epidemiology for students of clinical medicine. It is also usable for the students of other health professions such as nursing, dentistry, pharmacy, public health service etc. It also can be used as the reference book for other health professionals. For medical students, this book assumes that they have successfully finished a short course of medical statistics. 
In this textbook, most of the chapters in Part one are concentrated on the basic principles concepts and methodology of epidemiology (first 10 chapters). The remaining chapters in the second part consist of some applications of epidemiology. These may be selected by instructor for lecture or for used by students as selfreadings. 
It is important to note that this textbook just serves as an introduction of epidemiology. Because of the obvious constraints of any single textbook, it does not comprise an exhaustive answer to many questions in epidemiology. I would appreciate any suggestions on what and how the contents of this book can be improved. 
 
Wang Peishan 
Department of Epidemiology and Biostatistics 
School of Public Health 
Tianjin Medical University 
Tianjin, China 
psw@tijmu.edu.cn 
October 2014 
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流行病学(留学生与双语教学用)（英文版）（普通高等教育“十二五”规划教材·全国高等下载

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